Our computer model projects a victory for the Buffalo Bills when they face the Tennessee Titans at Highmark Stadium on Sunday, Oct. 20 at 1 p.m. ET — for a full breakdown regarding the spread, over/under and final score, see below.

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The Bills are averaging 27.5 points per game on offense this year (sixth in NFL), and they are giving up 21 points per game (11th) on the defensive side of the ball. From an offensive angle, the Titans are generating 19.2 points per game (22nd-ranked). They rank 13th in the NFL on defense (22 points surrendered per game).

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Titans vs. Bills Predictions and Picks

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Titans Betting Info

• Sportsbooks have implied with the moneyline set for this matchup that the Titans have a 21.1% chance to win.
• Tennessee has a record of just 1-4-0 against the spread this year.
• This year, games featuring Tennessee have hit the over twice.
• The over/under for this game is 0.9 points higher than the average scoring total for Titans games (playoffs included) of 40.1.

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Bills Betting Info

• The Bills have an 83.3% chance to win this matchup based on the moneyline’s implied probability.
• Buffalo has compiled a 3-3-0 record against the spread this season.
• A total of three out of six Buffalo games this season have gone over the point total.
• The point total average for Bills games this season is 46.1, 5.1 points higher than the over/under for this matchup.

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Titans vs. Bills 2024 Scoring Insights

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